1) The World Health Organization reports that being physically inactive comes in fourth as a leading risk factor for death. That’s Death with a capital D.

2) Sitting increases your risk of getting cancer in a very big way.
The American Institute for Cancer Research highlighted at its 2012 conference specific research findings showing that 49,000 cases of breast cancer and 43,000 cases of colon cancer in the U.S. could be linked to inactivity.

3) The Journal of Applied Physiology in 2011 revealed that when people lower their activity from over 10,000 steps a day to less than 5,000 steps a day, physical changes in the body directly increase that person’s risk of type 2 diabetes.

4) And finally studies are starting to show links between sitting too long and everything from increased risk of kidney disease, to a high risk for blood clots in the legs. In fact, the blood clot issue related to excessive computer use is becoming known in medical circles as “e-thrombosis”.

This was the first source of information we found.
http://www.makeuseof.com/tag/4-health-issues-sitting-long-avoid/

But don’t take our word for it. Do your own research.
Then consider taking a serious look at our Kibouti footrest and let us explain how it can be helpful not only in avoiding lower and upper back problems, help you deal with stress, but also help you do something about avoiding some of the issues described above.